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INFOSCALE
2006
ACM
15 years 6 months ago
Scalable hardware accelerator for comparing DNA and protein sequences
Abstract— Comparing genetic sequences is a well-known problem in bioinformatics. Newly determined sequences are being compared to known sequences stored in databases in order to ...
Philippe Faes, Bram Minnaert, Mark Christiaens, Er...
BMCBI
2006
132views more  BMCBI 2006»
15 years 15 days ago
Comprehensive quality control utilizing the prehybridization third-dye image leads to accurate gene expression measurements by c
Background: Gene expression profiling using microarrays has become an important genetic tool. Spotted arrays prepared in academic labs have the advantage of low cost and high desi...
Xujing Wang, Shuang Jia, Lisa Meyer, Bixia Xiang, ...
BMCBI
2006
108views more  BMCBI 2006»
15 years 15 days ago
Promoter prediction and annotation of microbial genomes based on DNA sequence and structural responses to superhelical stress
Background: In our previous studies, we found that the sites in prokaryotic genomes which are most susceptible to duplex destabilization under the negative superhelical stresses t...
Huiquan Wang, Craig J. Benham
118
Voted
BMCBI
2006
117views more  BMCBI 2006»
15 years 15 days ago
Gene Designer: a synthetic biology tool for constructing artificial DNA segments
Background: Direct synthesis of genes is rapidly becoming the most efficient way to make functional genetic constructs and enables applications such as codon optimization, RNAi re...
Alan Villalobos, Jon E. Ness, Claes Gustafsson, Je...
92
Voted
BMCBI
2007
147views more  BMCBI 2007»
15 years 13 days ago
Comparative analysis of long DNA sequences by per element information content using different contexts
Background: Features of a DNA sequence can be found by compressing the sequence under a suitable model; good compression implies low information content. Good DNA compression mode...
Trevor I. Dix, David R. Powell, Lloyd Allison, Jul...