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BMCBI
2006
98views more  BMCBI 2006»
14 years 10 months ago
Quantitative comparison of EST libraries requires compensation for systematic biases in cDNA generation
Background: Publicly accessible EST libraries contain valuable information that can be utilized for studies of tissue-specific gene expression and processing of individual genes. ...
Donglin Liu, Joel H. Graber
BMCBI
2006
114views more  BMCBI 2006»
14 years 10 months ago
BLISS: biding site level identification of shared signal-modules in DNA regulatory sequences
Background: Regulatory modules are segments of the DNA that control particular aspects of gene expression. Their identification is therefore of great importance to the field of mo...
Hailong Meng, Arunava Banerjee, Lei Zhou
88
Voted
BMCBI
2007
163views more  BMCBI 2007»
14 years 10 months ago
Use of genomic DNA control features and predicted operon structure in microarray data analysis: ArrayLeaRNA - a Bayesian approac
Background: Microarrays are widely used for the study of gene expression; however deciding on whether observed differences in expression are significant remains a challenge. Resul...
Carmen Pin, Mark Reuter
IMSCCS
2006
IEEE
15 years 4 months ago
Degenerated Primer Design to Amplify the Heavy Chain Variable Region from Immunoglobulin cDNA
Background: The amplification of variable regions of immunoglobulins has become a major challenge in the cloning of antibody genes, whether from hybridoma cell lines or splenic B ...
Wang Ying, Chen Wei, Li Xu, Cheng Bing
BMCBI
2006
136views more  BMCBI 2006»
14 years 10 months ago
EMD: an ensemble algorithm for discovering regulatory motifs in DNA sequences
Background: Understanding gene regulatory networks has become one of the central research problems in bioinformatics. More than thirty algorithms have been proposed to identify DN...
Jianjun Hu, Yifeng D. Yang, Daisuke Kihara