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85
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BMCBI
2006
156views more  BMCBI 2006»
14 years 10 months ago
Bayesian models for pooling microarray studies with multiple sources of replications
Background: Biologists often conduct multiple but different cDNA microarray studies that all target the same biological system or pathway. Within each study, replicate slides with...
Erin M. Conlon, Joon J. Song, Jun S. Liu
83
Voted
BMCBI
2006
102views more  BMCBI 2006»
14 years 10 months ago
UVPAR: fast detection of functional shifts in duplicate genes
Background: The imprint of natural selection on gene sequences is often difficult to detect. A plethora of methods have been devised to detect genetic changes due to selective pro...
Vicente Arnau, Miguel Gallach, J. Ignasi Lucas, Ig...
88
Voted
IJBRA
2006
92views more  IJBRA 2006»
14 years 10 months ago
Jumpstarting phylogenetic analysis
: Phylogenetic analysis is a central tool in studies of comparative genomics. When a new region of DNA is isolated and sequenced, researchers are often forced to throw away months ...
Jesse Mecham, Mark J. Clement, Quinn Snell, Todd F...
76
Voted
IJDMB
2006
90views more  IJDMB 2006»
14 years 10 months ago
An efficient motif discovery algorithm with unknown motif length and number of binding sites
: Most motif discovery algorithms from DNA sequences require the motif's length as input. Styczynski et al. introduced the Extended (l,d)-Motif Problem (EMP) where the motif&#...
Henry C. M. Leung, Francis Y. L. Chin
PRL
2006
130views more  PRL 2006»
14 years 10 months ago
Efficient huge-scale feature selection with speciated genetic algorithm
With increasing interest in bioinformatics, sophisticated tools are required to efficiently analyze gene information. The classification of gene expression profiles is crucial in ...
Jin-Hyuk Hong, Sung-Bae Cho