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BMCBI
2006
88views more  BMCBI 2006»
14 years 10 months ago
RiboSubstrates: a web application addressing the cleavage specificities of ribozymes in designated genomes
Background: RNA-dependent gene silencing is becoming a routine tool used in laboratories worldwide. One of the important remaining hurdles in the selection of the target sequence,...
Jean-François Lucier, Lucien Junior Bergero...
CANDC
2006
ACM
14 years 10 months ago
Dealing with repetitions in sequencing by hybridization
DNA sequencing by hybridization (SBH) induces errors in the biochemical experiment. Some of them are random and disappear when the experiment is repeated. Others are systematic, i...
Jacek Blazewicz, Fred Glover, Marta Kasprzak, Wojc...
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BIB
2006
141views more  BIB 2006»
14 years 10 months ago
Statistical significance in biological sequence analysis
One of the major goals of computational sequence analysis is to find sequence similarities, which could serve as evidence of structural and functional conservation, as well as of ...
Alexander Yu. Mitrophanov, Mark Borodovsky
ICCD
2006
IEEE
134views Hardware» more  ICCD 2006»
15 years 4 months ago
Automated Design of Microfluidics-Based Biochips: Connecting Biochemistry to Electronics CAD
Microfluidics-based biochips offer exciting possibilities for highthroughput sequencing, parallel immunoassays, blood chemistry for clinical diagnostics, DNA sequencing, and envir...
Krishnendu Chakrabarty
IPPS
2006
IEEE
15 years 4 months ago
Phylogenetic models of rate heterogeneity: a high performance computing perspective
Inference of phylogenetic trees using the maximum likelihood (ML) method is NP-hard. Furthermore, the computation of the likelihood function for huge trees of more than 1,000 orga...
Alexandros Stamatakis