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BMCBI
2007
128views more  BMCBI 2007»
14 years 9 months ago
Absolute estimation of initial concentrations of amplicon in a real-time RT-PCR process
Background: Since real time PCR was first developed, several approaches to estimating the initial quantity of template in an RT-PCR reaction have been tried. While initially only ...
Marjo V. Smith, Chris R. Miller, Michael Kohn, Nig...
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BMCBI
2007
136views more  BMCBI 2007»
14 years 9 months ago
Genomorama: genome visualization and analysis
Background: The ability to visualize genomic features and design experimental assays that can target specific regions of a genome is essential for modern biology. To assist in the...
Jason D. Gans, Murray Wolinsky
BMCBI
2007
113views more  BMCBI 2007»
14 years 9 months ago
CoryneRegNet 4.0 - A reference database for corynebacterial gene regulatory networks
Background: Detailed information on DNA-binding transcription factors (the key players in the regulation of gene expression) and on transcriptional regulatory interactions of micr...
Jan Baumbach
BMCBI
2007
173views more  BMCBI 2007»
14 years 9 months ago
Ringo - an R/Bioconductor package for analyzing ChIP-chip readouts
Background: Chromatin immunoprecipitation combined with DNA microarrays (ChIP-chip) is a high-throughput assay for DNA-protein-binding or post-translational chromatin/histone modi...
Joern Toedling, Oleg Sklyar, Tammo Krueger, Jenny ...
BMCBI
2007
135views more  BMCBI 2007»
14 years 9 months ago
Sequence similarity is more relevant than species specificity in probabilistic backtranslation
Background: Backtranslation is the process of decoding a sequence of amino acids into the corresponding codons. All synthetic gene design systems include a backtranslation module....
Alfredo Ferro, Rosalba Giugno, Giuseppe Pigola, Al...