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BIOINFORMATICS
2004
99views more  BIOINFORMATICS 2004»
14 years 9 months ago
EST clustering error evaluation and correction
Motivation: The gene expression intensity information conveyed by (EST) Expressed Sequence Tag data can be used to infer important cDNA library properties, such as gene number and...
Ji-Ping Z. Wang, Bruce G. Lindsay 0002, James Leeb...
BMCBI
2004
125views more  BMCBI 2004»
14 years 9 months ago
A fast algorithm for determining the best combination of local alignments to a query sequence
Background: Existing sequence alignment algorithms assume that similarities between DNA or amino acid sequences are linearly ordered. That is, stretches of similar nucleotides or ...
Gavin C. Conant, Andreas Wagner
BMCBI
2002
128views more  BMCBI 2002»
14 years 9 months ago
Correlating overrepresented upstream motifs to gene expression: a computational approach to regulatory element discovery in euka
Background: Gene regulation in eukaryotes is mainly effected through transcription factors binding to rather short recognition motifs generally located upstream of the coding regi...
Michele Caselle, Ferdinando Di Cunto, Paolo Prover...
BMCBI
2007
114views more  BMCBI 2007»
14 years 9 months ago
Large scale statistical inference of signaling pathways from RNAi and microarray data
Background: The advent of RNA interference techniques enables the selective silencing of biologically interesting genes in an efficient way. In combination with DNA microarray tec...
Holger Fröhlich, Mark Fellmann, Holger Sü...
VLDB
2007
ACM
113views Database» more  VLDB 2007»
15 years 9 months ago
Fast nGram-Based String Search Over Data Encoded Using Algebraic Signatures
We propose a novel string search algorithm for data stored once and read many times. Our search method combines the sublinear traversal of the record (as in Boyer Moore or Knuth-M...
Witold Litwin, Riad Mokadem, Philippe Rigaux, Thom...