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NC
2008
120views Neural Networks» more  NC 2008»
14 years 11 months ago
Combining self-healing and proofreading in self-assembly
Molecular self-assembly is a promising approach to bottom-up fabrication of complex structures. A major impediment to the practical use of self-assembly to create complex structure...
David Soloveichik, Matthew Cook, Erik Winfree
QUEUE
2007
63views more  QUEUE 2007»
14 years 11 months ago
The Code Delusion
st sacred importance of an abstract and one-dimensional genetic code—a code so thinly connected to the full-fleshed reality of our selves that its entire import could be captured...
Stan Kelly-Bootle
BMCBI
2008
95views more  BMCBI 2008»
14 years 12 months ago
Gene set analyses for interpreting microarray experiments on prokaryotic organisms
Background: Despite the widespread usage of DNA microarrays, questions remain about how best to interpret the wealth of gene-by-gene transcriptional levels that they measure. Rece...
Nathan L. Tintle, Aaron A. Best, Matthew DeJongh, ...
BMCBI
2008
107views more  BMCBI 2008»
14 years 12 months ago
Probe-specific mixed-model approach to detect copy number differences using multiplex ligation-dependent probe amplification (ML
Background: MLPA method is a potentially useful semi-quantitative method to detect copy number alterations in targeted regions. In this paper, we propose a method for the normaliz...
Juan R. González, Josep L. Carrasco, Llu&ia...
BMCBI
2008
125views more  BMCBI 2008»
14 years 12 months ago
SNPLims: a data management system for genome wide association studies
Background: Recent progresses in genotyping technologies allow the generation high-density genetic maps using hundreds of thousands of genetic markers for each DNA sample. The ava...
Alessandro Orro, Guia Guffanti, Erika Salvi, Fabio...