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NC
2008
120views Neural Networks» more  NC 2008»
14 years 9 months ago
Combining self-healing and proofreading in self-assembly
Molecular self-assembly is a promising approach to bottom-up fabrication of complex structures. A major impediment to the practical use of self-assembly to create complex structure...
David Soloveichik, Matthew Cook, Erik Winfree
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QUEUE
2007
63views more  QUEUE 2007»
14 years 9 months ago
The Code Delusion
st sacred importance of an abstract and one-dimensional genetic code—a code so thinly connected to the full-fleshed reality of our selves that its entire import could be captured...
Stan Kelly-Bootle
BMCBI
2008
95views more  BMCBI 2008»
14 years 9 months ago
Gene set analyses for interpreting microarray experiments on prokaryotic organisms
Background: Despite the widespread usage of DNA microarrays, questions remain about how best to interpret the wealth of gene-by-gene transcriptional levels that they measure. Rece...
Nathan L. Tintle, Aaron A. Best, Matthew DeJongh, ...
BMCBI
2008
107views more  BMCBI 2008»
14 years 9 months ago
Probe-specific mixed-model approach to detect copy number differences using multiplex ligation-dependent probe amplification (ML
Background: MLPA method is a potentially useful semi-quantitative method to detect copy number alterations in targeted regions. In this paper, we propose a method for the normaliz...
Juan R. González, Josep L. Carrasco, Llu&ia...
BMCBI
2008
125views more  BMCBI 2008»
14 years 9 months ago
SNPLims: a data management system for genome wide association studies
Background: Recent progresses in genotyping technologies allow the generation high-density genetic maps using hundreds of thousands of genetic markers for each DNA sample. The ava...
Alessandro Orro, Guia Guffanti, Erika Salvi, Fabio...