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BMCBI
2008
117views more  BMCBI 2008»
14 years 9 months ago
RNACompress: Grammar-based compression and informational complexity measurement of RNA secondary structure
Background: With the rapid emergence of RNA databases and newly identified non-coding RNAs, an efficient compression algorithm for RNA sequence and structural information is neede...
Qi Liu, Yu Yang, Chun Chen, Jiajun Bu, Yin Zhang, ...
BMCBI
2008
144views more  BMCBI 2008»
14 years 9 months ago
Local conservation scores without a priori assumptions on neutral substitution rates
Background: Comparative genomics aims to detect signals of evolutionary conservation as an indicator of functional constraint. Surprisingly, results of the ENCODE project revealed...
Janis Dingel, Pavol Hanus, Niccolò Leonardi...
BMCBI
2008
193views more  BMCBI 2008»
14 years 9 months ago
Missing value imputation for microarray gene expression data using histone acetylation information
Background: It is an important pre-processing step to accurately estimate missing values in microarray data, because complete datasets are required in numerous expression profile ...
Qian Xiang, Xianhua Dai, Yangyang Deng, Caisheng H...
BMCBI
2008
200views more  BMCBI 2008»
14 years 9 months ago
Defining functional distances over Gene Ontology
Background: A fundamental problem when trying to define the functional relationships between proteins is the difficulty in quantifying functional similarities, even when well-stru...
Angela del Pozo, Florencio Pazos, Alfonso Valencia
BMCBI
2008
112views more  BMCBI 2008»
14 years 9 months ago
GlycomeDB - integration of open-access carbohydrate structure databases
Background: Although carbohydrates are the third major class of biological macromolecules, after proteins and DNA, there is neither a comprehensive database for carbohydrate struc...
René Ranzinger, Stephan Herget, Thomas Wett...