Performance of DNA sequencing-by-synthesis systems is fundamentally limited by the stochastic nature of the underlying biochemical process. We develop a novel graphical representa...
Hairpin completion is an abstract operation modeling a DNA biooperation which receives as input a DNA strand w = xαyα, and outputs w = xαy¯αx, where x denotes the Watson-Cric...
The initiation and regulation of transcription in eukaryotes is complex and involves a large number of transcription factors (TFs), which are known to bind to the regulatory regio...
Ulf Schaefer, Sebastian Schmeier, Vladimir B. Baji...
Background: Second generation sequencing technologies yield DNA sequence data at ultra high-throughput. Common to most biological applications is a mapping of the reads to an almo...
Manuel Holtgrewe, Anne-Katrin Emde, David Weese, K...
—We propose an extension of van Lamsweerde’s goal-oriented requirements engineering to the domain of programmable DNA nanotechnology. This is a domain in which individual devic...
Robyn R. Lutz, Jack H. Lutz, James I. Lathrop, Tit...