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ICASSP
2011
IEEE
12 years 10 months ago
Message-passing for base-calling in sequencing-by-synthesis systems
Performance of DNA sequencing-by-synthesis systems is fundamentally limited by the stochastic nature of the underlying biochemical process. We develop a novel graphical representa...
Sang Hyun Lee, Manohar Shamaiah, Haris Vikalo
CORR
2011
Springer
193views Education» more  CORR 2011»
13 years 1 months ago
On the regularity of iterated hairpin completion of a single word
Hairpin completion is an abstract operation modeling a DNA biooperation which receives as input a DNA strand w = xαyα, and outputs w = xαy¯αx, where x denotes the Watson-Cric...
Lila Kari, Steffen Kopecki, Shinnosuke Seki
NAR
2011
186views Computer Vision» more  NAR 2011»
12 years 9 months ago
TcoF-DB: dragon database for human transcription co-factors and transcription factor interacting proteins
The initiation and regulation of transcription in eukaryotes is complex and involves a large number of transcription factors (TFs), which are known to bind to the regulatory regio...
Ulf Schaefer, Sebastian Schmeier, Vladimir B. Baji...
BMCBI
2011
12 years 10 months ago
A Novel And Well-Defined Benchmarking Method For Second Generation Read Mapping
Background: Second generation sequencing technologies yield DNA sequence data at ultra high-throughput. Common to most biological applications is a mapping of the reads to an almo...
Manuel Holtgrewe, Anne-Katrin Emde, David Weese, K...
ICSE
2012
IEEE-ACM
11 years 8 months ago
Engineering and verifying requirements for programmable self-assembling nanomachines
—We propose an extension of van Lamsweerde’s goal-oriented requirements engineering to the domain of programmable DNA nanotechnology. This is a domain in which individual devic...
Robyn R. Lutz, Jack H. Lutz, James I. Lathrop, Tit...