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NAR
2011
212views Computer Vision» more  NAR 2011»
14 years 18 days ago
The Sequence Read Archive
The combination of significantly lower cost and increased speed of sequencing has resulted in an explosive growth of data submitted into the primary next-generation sequence data ...
Rasko Leinonen, Hideaki Sugawara, Martin Shumway
BMCBI
2011
14 years 1 months ago
Efficient alignment of pyrosequencing reads for re-sequencing applications
Background: Over the past few years, new massively parallel DNA sequencing technologies have emerged. These platforms generate massive amounts of data per run, greatly reducing th...
Francisco Fernandes, Paulo G. S. da Fonseca, Lu&ia...
DNA
2011
Springer
227views Bioinformatics» more  DNA 2011»
13 years 9 months ago
Cooperative Assembly Systems
Several molecular systems form large-scale objects. One would like to understand their assembly and how this assembly is regulated. As a first step, we investigate the phase trans...
Vincent Danos, Heinz Koeppl, John Wilson-Kanamori
BMCBI
2011
14 years 1 months ago
A Beta-Mixture Model for Dimensionality Reduction, Sample Classification and Analysis
Background: Patterns of genome-wide methylation vary between tissue types. For example, cancer tissue shows markedly different patterns from those of normal tissue. In this paper ...
Kirsti Laurila, Bodil Oster, Claus L. Andersen, Ph...
BMCBI
2011
14 years 1 months ago
Combinatorial analysis and algorithms for quasispecies reconstruction using next-generation sequencing
Background: Next-generation sequencing (NGS) offers a unique opportunity for high-throughput genomics and has potential to replace Sanger sequencing in many fields, including de-n...
Mattia C. F. Prosperi, Luciano Prosperi, Alessandr...