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117
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BMCBI
2010
15 years 4 months ago
2010
Background: The success achieved by genome-wide association (GWA) studies in the identification of candidate loci for complex diseases has been accompanied by an inability to expl...
146
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BMCBI
2010
15 years 4 months ago
2010
Background: While the pairwise alignments produced by sequence similarity searches are a powerful tool for identifying homologous proteins - proteins that share a common ancestor ...
142
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BMCBI
2010
15 years 4 months ago
2010
Background: Accurately covering the conformational space of amino acid side chains is essential for important applications such as protein design, docking and high resolution stru...
125
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BMCBI
2010
15 years 4 months ago
2010
Background: To develop protein therapeutics from exogenous sources, it is necessary to mitigate the risks of eliciting an anti-biotherapeutic immune response. A key aspect of the ...
135
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BMCBI
2010
15 years 4 months ago
2010
Background: In the current era of scientific research, efficient communication of information is paramount. As such, the nature of scholarly and scientific communication is changi...