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154
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BMCBI
2006
15 years 4 months ago
2006
Background: After complete sequencing of a number of genomes the focus has now turned to proteomics. Advanced proteomics technologies such as two-hybrid assay, mass spectrometry e...
149
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BMCBI
2006
15 years 4 months ago
2006
Background: When accurate models for the divergent evolution of protein sequences are integrated with complementary biological information, such as folded protein structures, anal...
139
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BMCBI
2006
15 years 4 months ago
2006
Background: Benchmarking algorithms in structural bioinformatics often involves the construction of datasets of proteins with given sequence and structural properties. The SCOP da...
120
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BMCBI
2006
15 years 4 months ago
2006
Background: That the structure determines the function of proteins is a central paradigm in biology. However, protein functions are more directly related to cooperative effects at...
161
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BMCBI
2006
15 years 4 months ago
2006
Background: Recent advances with high-throughput methods in life-science research have increased the need for automatized data analysis and visual exploration techniques. Sophisti...