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117
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BMCBI
2004
150views more  BMCBI 2004»
15 years 20 days ago
Rank Difference Analysis of Microarrays (RDAM), a novel approach to statistical analysis of microarray expression profiling data
Background: A key step in the analysis of microarray expression profiling data is the identification of genes that display statistically significant changes in expression signals ...
Dietmar E. Martin, Philippe Demougin, Michael N. H...
121
Voted
BMCBI
2004
95views more  BMCBI 2004»
15 years 20 days ago
PCOGR: Phylogenetic COG ranking as an online tool to judge the specificity of COGs with respect to freely definable groups of or
Background: The rapidly increasing number of completely sequenced genomes led to the establishment of the COG-database which, based on sequence homologies, assigns similar protein...
Florian Meereis, Michael Kaufmann
BMCBI
2004
113views more  BMCBI 2004»
15 years 20 days ago
Oligo kernels for datamining on biological sequences: a case study on prokaryotic translation initiation sites
Background: Kernel-based learning algorithms are among the most advanced machine learning methods and have been successfully applied to a variety of sequence classification tasks ...
Peter Meinicke, Maike Tech, Burkhard Morgenstern, ...
117
Voted
BMCBI
2004
91views more  BMCBI 2004»
15 years 20 days ago
SIGI: score-based identification of genomic islands
Background: Genomic islands can be observed in many microbial genomes. These stretches of DNA have a conspicuous composition with regard to sequence or encoded functions. Genomic ...
Rainer Merkl
106
Voted
BMCBI
2004
104views more  BMCBI 2004»
15 years 20 days ago
Discriminative topological features reveal biological network mechanisms
Background: Recent genomic and bioinformatic advances have motivated the development of numerous network models intending to describe graphs of biological, technological, and soci...
Manuel Middendorf, Etay Ziv, Carter Adams, Jen Hom...
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