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    BMCBI
    2008
    121views more  BMCBI 2008»
    Stability of gene contributions and identification of outliers in multivariate analysis of microarray data
    14 years 9 months ago
    Stability of gene contributions and identification of outliers in multivariate analysis of microarray data
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    Background: Multivariate ordination methods are powerful tools for the exploration of complex data structures present in microarray data. These methods have several advantages com...
    Florent Baty, Daniel Jaeger, Frank Preiswerk, Mart...
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    BMCBI
    2008
    176views more  BMCBI 2008»
    H2r: Identification of evolutionary important residues by means of an entropy based analysis of multiple sequence alignments
    14 years 9 months ago
    H2r: Identification of evolutionary important residues by means of an entropy based analysis of multiple sequence alignments
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    Background: A multiple sequence alignment (MSA) generated for a protein can be used to characterise residues by means of a statistical analysis of single columns. In addition to t...
    Rainer Merkl, Matthias Zwick
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    BMCBI
    2008
    129views more  BMCBI 2008»
    Gene set enrichment analysis for non-monotone association and multiple experimental categories
    14 years 9 months ago
    Gene set enrichment analysis for non-monotone association and multiple experimental categories
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    Background: Recently, microarray data analyses using functional pathway information, e.g., gene set enrichment analysis (GSEA) and significance analysis of function and expression...
    Rongheng Lin, Shuangshuang Dai, Richard D. Irwin, ...
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    BMCBI
    2008
    108views more  BMCBI 2008»
    Supervised Lowess normalization of comparative genome hybridization data - application to lactococcal strain comparisons
    14 years 9 months ago
    Supervised Lowess normalization of comparative genome hybridization data - application to lactococcal strain comparisons
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    Background: Array-based comparative genome hybridization (aCGH) is commonly used to determine the genomic content of bacterial strains. Since prokaryotes in general have less cons...
    Sacha A. F. T. van Hijum, Richard J. S. Baerends, ...
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    BMCBI
    2008
    123views more  BMCBI 2008»
    A tree-based conservation scoring method for short linear motifs in multiple alignments of protein sequences
    14 years 9 months ago
    A tree-based conservation scoring method for short linear motifs in multiple alignments of protein sequences
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    Background: The structure of many eukaryotic cell regulatory proteins is highly modular. They are assembled from globular domains, segments of natively disordered polypeptides and...
    Claudia Chica, Alberto Labarga, Cathryn M. Gould, ...
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