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BMCBI
2006
14 years 9 months ago
2006
Background: In the Bioinformatics field, a great deal of interest has been given to Non-negative matrix factorization technique (NMF), due to its capability of providing new insig...
BMCBI
2006
14 years 9 months ago
2006
Background: Feature selection is an approach to overcome the 'curse of dimensionality' in complex researches like disease classification using microarrays. Statistical m...
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BMCBI
2006
14 years 9 months ago
2006
Background: The subcellular location of a protein is closely related to its function. It would be worthwhile to develop a method to predict the subcellular location for a given pr...
BMCBI
2006
14 years 9 months ago
2006
Background: Quantitative descriptions of amino acid similarity, expressed as probabilistic models of evolutionary interchangeability, are central to many mainstream bioinformatic ...
BMCBI
2006
14 years 9 months ago
2006
Background: Normalization of gene expression microarrays carrying thousands of genes is based on assumptions that do not hold for diagnostic microarrays carrying only few genes. T...