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BMCBI
2006
84views more  BMCBI 2006»
14 years 12 months ago
Inferring topology from clustering coefficients in protein-protein interaction networks
Background: Although protein-protein interaction networks determined with high-throughput methods are incomplete, they are commonly used to infer the topology of the complete inte...
Caroline C. Friedel, Ralf Zimmer
BMCBI
2006
119views more  BMCBI 2006»
14 years 12 months ago
Evaluation of microarray data normalization procedures using spike-in experiments
Background: Recently, a large number of methods for the analysis of microarray data have been proposed but there are few comparisons of their relative performances. By using so-ca...
Patrik Rydén, Henrik Andersson, Mattias Lan...
BMCBI
2007
194views more  BMCBI 2007»
14 years 12 months ago
A meta-data based method for DNA microarray imputation
Background: DNA microarray experiments are conducted in logical sets, such as time course profiling after a treatment is applied to the samples, or comparisons of the samples unde...
Rebecka Jörnsten, Ming Ouyang, Hui-Yu Wang
BMCBI
2007
187views more  BMCBI 2007»
14 years 12 months ago
BioWMS: a web-based Workflow Management System for bioinformatics
Background: An in-silico experiment can be naturally specified as a workflow of activities implementing, in a standardized environment, the process of data and control analysis. A...
Ezio Bartocci, Flavio Corradini, Emanuela Merelli,...
BMCBI
2007
59views more  BMCBI 2007»
14 years 12 months ago
Environment specific substitution tables for thermophilic proteins
Background: Thermophilic organisms are able to live at high temperatures ranging from 50 to > 100°C. Their proteins must be sufficiently stable to function under these extreme...
K. Mizuguchi, M. Sele, Maria Vittoria Cubellis