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79
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BMCBI
2005
190views more  BMCBI 2005»
14 years 9 months ago
Species-specific analysis of protein sequence motifs using mutual information
Background: Protein sequence motifs are by definition short fragments of conserved amino acids, often associated with a specific function. Accordingly protein sequence profiles de...
Jan Hummel, Nima Keshvari, Wolfram Weckwerth, Joac...
86
Voted
BMCBI
2005
73views more  BMCBI 2005»
14 years 9 months ago
An analysis of extensible modelling for functional genomics data
Background: Several data formats have been developed for large scale biological experiments, using a variety of methodologies. Most data formats contain a mechanism for allowing e...
Andrew R. Jones, Norman W. Paton
BMCBI
2005
136views more  BMCBI 2005»
14 years 9 months ago
Automatic detection of false annotations via binary property clustering
Background: Computational protein annotation methods occasionally introduce errors. Falsepositive (FP) errors are annotations that are mistakenly associated with a protein. Such f...
Noam Kaplan, Michal Linial
BMCBI
2005
94views more  BMCBI 2005»
14 years 9 months ago
Measuring similarities between transcription factor binding sites
Background: Collections of transcription factor binding profiles (Transfac, Jaspar) are essential to identify regulatory elements in DNA sequences. Subsets of highly similar profi...
Szymon M. Kielbasa, Didier Gonze, Hanspeter Herzel
BMCBI
2005
132views more  BMCBI 2005»
14 years 9 months ago
Kalign - an accurate and fast multiple sequence alignment algorithm
Background: The alignment of multiple protein sequences is a fundamental step in the analysis of biological data. It has traditionally been applied to analyzing protein families f...
Timo Lassmann, Erik L. L. Sonnhammer