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BMCBI
2007
173views more  BMCBI 2007»
14 years 12 months ago
Recursive Cluster Elimination (RCE) for classification and feature selection from gene expression data
Background: Classification studies using gene expression datasets are usually based on small numbers of samples and tens of thousands of genes. The selection of those genes that a...
Malik Yousef, Segun Jung, Louise C. Showe, Michael...
BMCBI
2007
100views more  BMCBI 2007»
14 years 11 months ago
Discovering structural motifs using a structural alphabet: Application to magnesium-binding sites
Background: For many metalloproteins, sequence motifs characteristic of metal-binding sites have not been found or are so short that they would not be expected to be metal-specifi...
Minko Dudev, Carmay Lim
BMCBI
2007
113views more  BMCBI 2007»
14 years 11 months ago
Statistical tools for transgene copy number estimation based on real-time PCR
Background: As compared with traditional transgene copy number detection technologies such as Southern blot analysis, real-time PCR provides a fast, inexpensive and high-throughpu...
Joshua S. Yuan, Jason N. Burris, Nathan R. Stewart...
BMCBI
2007
101views more  BMCBI 2007»
14 years 11 months ago
Gene expression changes induced by the tumorigenic pyrrolizidine alkaloid riddelliine in liver of Big Blue rats
Background: Pyrrolizidine alkaloids (PAs) are probably the most common plant constituents that poison livestock, wildlife, and humans worldwide. Riddelliine is isolated from plant...
Nan Mei, Lei Guo, Ruqing Liu, James C. Fuscoe, Tao...
BMCBI
2007
177views more  BMCBI 2007»
14 years 11 months ago
The BioPrompt-box: an ontology-based clustering tool for searching in biological databases
Background: High-throughput molecular biology provides new data at an incredible rate, so that the increase in the size of biological databanks is enormous and very rapid. This sc...
Claudio Corsi, Paolo Ferragina, Roberto Marangoni