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BMCBI
2010
14 years 9 months ago
2010
Background: The analysis of oligonucleotide microarray data in pathogen surveillance and discovery is a challenging task. Target template concentration, nucleic acid integrity, an...
BMCBI
2010
14 years 9 months ago
2010
Background: High-resolution tandem mass spectra can now be readily acquired with hybrid instruments, such as LTQ-Orbitrap and LTQ-FT, in high-throughput shotgun proteomics workflo...
BMCBI
2010
14 years 9 months ago
2010
Background: High-throughput genotyping microarrays assess both total DNA copy number and allelic composition, which makes them a tool of choice for copy number studies in cancer, ...
BMCBI
2010
14 years 9 months ago
2010
Background: DNA copy number aberration (CNA) is very important in the pathogenesis of tumors and other diseases. For example, CNAs may result in suppression of anti-oncogenes and ...
BMCBI
2010
14 years 9 months ago
2010
Background: Tiling-arrays are applicable to multiple types of biological research questions. Due to its advantages (high sensitivity, resolution, unbiased), the technology is ofte...