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ALMOB
2007
151views more  ALMOB 2007»
14 years 10 months ago
Local sequence alignments statistics: deviations from Gumbel statistics in the rare-event tail
Background: The optimal score for ungapped local alignments of infinitely long random sequences is known to follow a Gumbel extreme value distribution. Less is known about the imp...
Stefan Wolfsheimer, Bernd Burghardt, Alexander K. ...
AOR
2007
107views more  AOR 2007»
14 years 9 months ago
Job Shop Scheduling with Unit Length Tasks: Bounds and Algorithms
We consider the job shop scheduling problem unit−Jm, where each job is processed once on each of m given machines. Every job consists of a permutation of tasks for all machines....
Juraj Hromkovic, Tobias Mömke, Kathleen Stein...
BIOINFORMATICS
2007
117views more  BIOINFORMATICS 2007»
14 years 9 months ago
Mining biological networks for unknown pathways
Biological pathways provide significant insights on the interaction mechanisms of molecules. Presently, many essential pathways still remain unknown or incomplete for newly sequen...
Ali Cakmak, Gultekin Özsoyoglu
BMCBI
2007
154views more  BMCBI 2007»
14 years 9 months ago
Cinteny: flexible analysis and visualization of synteny and genome rearrangements in multiple organisms
Background: Identifying syntenic regions, i.e., blocks of genes or other markers with evolutionary conserved order, and quantifying evolutionary relatedness between genomes in ter...
Amit U. Sinha, Jaroslaw Meller
BMCBI
2007
134views more  BMCBI 2007»
14 years 9 months ago
Automatic generation of 3D motifs for classification of protein binding sites
Background: Since many of the new protein structures delivered by high-throughput processes do not have any known function, there is a need for structure-based prediction of prote...
Jean-Christophe Nebel, Pawel Herzyk, David R. Gilb...