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BMCBI
2007
111views more  BMCBI 2007»
14 years 9 months ago
MotifCombinator: a web-based tool to search for combinations of cis-regulatory motifs
Background: A combination of multiple types of transcription factors and cis-regulatory elements is often required for gene expression in eukaryotes, and the combinatorial regulat...
Mamoru Kato, Tatsuhiko Tsunoda
BMCBI
2007
108views more  BMCBI 2007»
14 years 9 months ago
Design and implementation of a generalized laboratory data model
Background: Investigators in the biological sciences continue to exploit laboratory automation methods and have dramatically increased the rates at which they can generate data. I...
Michael C. Wendl, Scott Smith, Craig S. Pohl, Davi...
BMCBI
2007
154views more  BMCBI 2007»
14 years 9 months ago
h-Profile plots for the discovery and exploration of patterns in gene expression data with an application to time course data
Background: An ever increasing number of techniques are being used to find genes with similar profiles from microarray studies. Visualization of gene expression profiles can aid t...
Yvonne E. Pittelkow, Susan R. Wilson
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BMCBI
2007
124views more  BMCBI 2007»
14 years 9 months ago
BranchClust: a phylogenetic algorithm for selecting gene families
Background: Automated methods for assembling families of orthologous genes include those based on sequence similarity scores and those based on phylogenetic approaches. The first ...
Maria S. Poptsova, J. Peter Gogarten
BMCBI
2007
141views more  BMCBI 2007»
14 years 9 months ago
A novel approach to detect hot-spots in large-scale multivariate data
Background: Progressive advances in the measurement of complex multifactorial components of biological processes involving both spatial and temporal domains have made it difficult...
Jianhua Wu, Keith M. Kendrick, Jianfeng Feng