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BMCBI
2007
123views more  BMCBI 2007»
14 years 12 months ago
BIRCH: A user-oriented, locally-customizable, bioinformatics system
Background: Molecular biologists need sophisticated analytical tools which often demand extensive computational resources. While finding, installing, and using these tools can be ...
Brian Fristensky
BMCBI
2007
104views more  BMCBI 2007»
14 years 12 months ago
Using contextual and lexical features to restructure and validate the classification of biomedical concepts
Background: Biomedical ontologies are critical for integration of data from diverse sources and for use by knowledge-based biomedical applications, especially natural language pro...
Jung-Wei Fan, Hua Xu, Carol Friedman
BMCBI
2007
78views more  BMCBI 2007»
14 years 12 months ago
Improved human disease candidate gene prioritization using mouse phenotype
Background: The majority of common diseases are multi-factorial and modified by genetically and mechanistically complex polygenic interactions and environmental factors. High-thro...
Jing Chen, Huan Xu, Bruce J. Aronow, Anil G. Jegga
BMCBI
2007
165views more  BMCBI 2007»
14 years 12 months ago
Automatic reconstruction of a bacterial regulatory network using Natural Language Processing
Background: Manual curation of biological databases, an expensive and labor-intensive process, is essential for high quality integrated data. In this paper we report the implement...
Carlos Rodríguez Penagos, Heladia Salgado, ...
BMCBI
2007
102views more  BMCBI 2007»
14 years 12 months ago
A mixture of feature experts approach for protein-protein interaction prediction
High-throughput methods can directly detect the set of interacting proteins in yeast but the results are often incomplete and exhibit high false positive and false negative rates....
Yanjun Qi, Judith Klein-Seetharaman, Ziv Bar-Josep...