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147
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BMCBI
2010
15 years 5 months ago
2010
Background: Quantitative trait locus (QTL) mapping identifies genomic regions that likely contain genes regulating a quantitative trait. However, QTL regions may encompass tens to...
143
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BMCBI
2010
15 years 5 months ago
2010
Background: Transcription Factors (TFs) and microRNAs (miRNAs) are key players for gene expression regulation in higher eukaryotes. In the last years, a large amount of bioinforma...
151
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BMCBI
2010
15 years 5 months ago
2010
Background: Direct in vivo investigation of human metabolism is complicated by the distinct metabolic functions of various sub-cellular organelles. Diverse micro-environments in d...
184
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BMCBI
2010
15 years 5 months ago
2010
Background: Genome-wide association studies (GWAS) using Copy Number Variation (CNV) are becoming a central focus of genetic research. CNVs have successfully provided target genom...
162
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BMCBI
2010
15 years 5 months ago
2010
Background: High throughput sequencing has become an increasingly important tool for biological research. However, the existing software systems for managing and processing these ...