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110
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BMCBI
2010
153views more  BMCBI 2010»
15 years 21 days ago
Starr: Simple Tiling ARRay analysis of Affymetrix ChIP-chip data
Background: Chromatin immunoprecipitation combined with DNA microarrays (ChIP-chip) is an assay used for investigating DNA-protein-binding or post-translational chromatin/histone ...
Benedikt Zacher, Pei Fen Kuan, Achim Tresch
BMCBI
2010
136views more  BMCBI 2010»
15 years 21 days ago
SCPS: a fast implementation of a spectral method for detecting protein families on a genome-wide scale
Background: An important problem in genomics is the automatic inference of groups of homologous proteins from pairwise sequence similarities. Several approaches have been proposed...
Tamás Nepusz, Rajkumar Sasidharan, Alberto ...
105
Voted
BMCBI
2010
100views more  BMCBI 2010»
15 years 21 days ago
Partitioning of copy-number genotypes in pedigrees
Background: Copy number variations (CNVs) and polymorphisms (CNPs) have only recently gained the genetic community's attention. Conservative estimates have shown that CNVs an...
Louis-Philippe Lemieux Perreault, Gregor U. Andelf...
BMCBI
2010
131views more  BMCBI 2010»
15 years 21 days ago
A comparison of approximation techniques for variance-based sensitivity analysis of biochemical reaction systems
Background: Sensitivity analysis is an indispensable tool for the analysis of complex systems. In a recent paper, we have introduced a thermodynamically consistent variance-based ...
Hong-Xuan Zhang, John Goutsias
104
Voted
BMCBI
2010
84views more  BMCBI 2010»
15 years 21 days ago
Word add-in for ontology recognition: semantic enrichment of scientific literature
Background: In the current era of scientific research, efficient communication of information is paramount. As such, the nature of scholarly and scientific communication is changi...
J. Lynn Fink, Pablo Fernicola, Rahul Chandran, Sav...