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BIOINFORMATICS
2006
14 years 10 months ago
2006
Motivation: Most previous approaches to model biochemical networks havefocusedeither on the characterization of a networkstructurewith a number of components or on the estimation ...
BMCBI
2006
14 years 10 months ago
2006
Background: The design of oligonucleotides and PCR primers for studying large genomes is complicated by the redundancy of sequences. The eukaryotic genomes are particularly diffic...
BMCBI
2006
14 years 10 months ago
2006
Background: Successful realization of a "systems biology" approach to analyzing cells is a grand challenge for our understanding of life. However, current modeling appro...
BMCBI
2006
14 years 10 months ago
2006
Background: Biochemically detailed stoichiometric matrices have now been reconstructed for various bacteria, yeast, and for the human cardiac mitochondrion based on genomic and pr...
BMCBI
2006
14 years 10 months ago
2006
Background:Receptors and scaffold proteins possess a number of distinct domains and bind multiple partners. A common problem in modeling signaling systems arises from a combinator...