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BMCBI
2008
113views more  BMCBI 2008»
15 years 18 days ago
SNPFile - A software library and file format for large scale association mapping and population genetics studies
Background: High-throughput genotyping technology has enabled cost effective typing of thousands of individuals in hundred of thousands of markers for use in genome wide studies. ...
Jesper Nielsen, Thomas Mailund
87
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BMCBI
2008
109views more  BMCBI 2008»
15 years 18 days ago
ConStruct: Improved construction of RNA consensus structures
Background: Aligning homologous non-coding RNAs (ncRNAs) correctly in terms of sequence and structure is an unresolved problem, due to both mathematical complexity and imperfect s...
Andreas Wilm, Kornelia Linnenbrink, Gerhard Steger
BMCBI
2008
111views more  BMCBI 2008»
15 years 18 days ago
SciDBMaker: new software for computer-aided design of specialized biological databases
Background: The exponential growth of research in molecular biology has brought concomitant proliferation of databases for stocking its findings. A variety of protein sequence dat...
Riadh Hammami, Abdelmajid Zouhir, Karim Naghmouchi...
117
Voted
BMCBI
2008
169views more  BMCBI 2008»
15 years 18 days ago
CompMoby: Comparative MobyDick for detection of cis-regulatory motifs
Background: The regulation of gene expression is complex and occurs at many levels, including transcriptional and post-transcriptional, in metazoans. Transcriptional regulation is...
Christina Chaivorapol, Collin Melton, Grace Wei, R...
107
Voted
BMCBI
2008
144views more  BMCBI 2008»
15 years 18 days ago
WGCNA: an R package for weighted correlation network analysis
Background: Correlation networks are increasingly being used in bioinformatics applications. For example, weighted gene co-expression network analysis is a systems biology method ...
Peter Langfelder, Steve Horvath