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JCB
2000
14 years 11 months ago
2000
A new method for detecting remote protein homologies is introduced and shown to perform well in classifying protein domains by SCOP superfamily. The method is a variant of support...
JCB
2000
14 years 11 months ago
2000
We study the problem of similarity detection by sequence alignment with gaps, using a recently established theoretical framework based on the morphology of alignment paths. Alignm...
JCB
2000
14 years 11 months ago
2000
For aligning DNA sequences that differ only by sequencing errors, or by equivalent errors from other sources, a greedy algorithm can be much faster than traditional dynamic progra...
JCB
2000
14 years 11 months ago
2000
It has been postulated that existing species have been linked in the past in a way that can be described using an additive tree structure. Any such tree structure reflecting speci...
JCB
2000
14 years 11 months ago
2000
Large scale gene duplication is a major force driving the evolution of genetic functional innovation. Whole genome duplications are widely believed to have played an important rol...