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BMCBI
2010
2010
Towards the systematic discovery of signal transduction networks using phosphorylation dynamics data
14 years 10 months ago
Background: Phosphorylation is a ubiquitous and fundamental regulatory mechanism that controls signal transduction in living cells. The number of identified phosphoproteins and th...
BMCBI
2010
14 years 10 months ago
2010
Background: Recent advances in proteomics technologies such as SELDI-TOF mass spectrometry has shown promise in the detection of early stage cancers. However, dimensionality reduc...
BMCBI
2010
14 years 10 months ago
2010
Background: Caspases are a family of proteases that have central functions in programmed cell death (apoptosis) and inflammation. Caspases mediate their effects through aspartate-...
BMCBI
2010
14 years 10 months ago
2010
Background: Tandem mass spectrometry (MS/MS) has become the primary way for protein identification in proteomics. A good score function for measuring the match quality between a p...
SIAMMA
2010
14 years 4 months ago
2010
In recent work nonlinear subdivision schemes which operate on manifold-valued data have been successfully analyzed with the aid of so-called proximity conditions bounding the diffe...