This paper presents an efficient computational method to identify a local symmetry axis in 3-dimensional viral structures obtained using electron cryomicroscopy. Local symmetry is...
Background: In studies that use DNA arrays to assess changes in gene expression, our goal is to evaluate the statistical significance of treatments on sets of genes. Genes can be ...
Background: A number of methods that use both protein structural and evolutionary information are available to predict the functional consequences of missense mutations. However, ...
Chris J. Needham, James R. Bradford, Andrew J. Bul...
We present a Two-Stage Machine Learning (ML) model as a data mining method to develop practice guidelines and apply it to the problem of dementia staging. Dementia staging in clin...
Subramani Mani, William Rodman Shankle, Malcolm B....
Background: Alternative splicing is an efficient mechanism for increasing the variety of functions fulfilled by proteins in a living cell. It has been previously demonstrated that...
Marc N. Offman, Ramil N. Nurtdinov, Mikhail S. Gel...