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BMCBI
2005
156views more  BMCBI 2005»
14 years 11 months ago
DynGO: a tool for visualizing and mining of Gene Ontology and its associations
Background: A large volume of data and information about genes and gene products has been stored in various molecular biology databases. A major challenge for knowledge discovery ...
Hongfang Liu, Zhang-Zhi Hu, Cathy H. Wu
BMCBI
2005
190views more  BMCBI 2005»
14 years 11 months ago
An Entropy-based gene selection method for cancer classification using microarray data
Background: Accurate diagnosis of cancer subtypes remains a challenging problem. Building classifiers based on gene expression data is a promising approach; yet the selection of n...
Xiaoxing Liu, Arun Krishnan, Adrian Mondry
BMCBI
2005
122views more  BMCBI 2005»
14 years 11 months ago
Quantitative analysis of EGR proteins binding to DNA: assessing additivity in both the binding site and the protein
Background: Recognition codes for protein-DNA interactions typically assume that the interacting positions contribute additively to the binding energy. While this is known to not ...
Jiajian Liu, Gary D. Stormo
BMCBI
2005
103views more  BMCBI 2005»
14 years 11 months ago
Quadratic regression analysis for gene discovery and pattern recognition for non-cyclic short time-course microarray experiments
Background: Cluster analyses are used to analyze microarray time-course data for gene discovery and pattern recognition. However, in general, these methods do not take advantage o...
Hua Liu, Sergey Tarima, Aaron S. Borders, Thomas V...
BMCBI
2005
201views more  BMCBI 2005»
14 years 11 months ago
Principal component analysis for predicting transcription-factor binding motifs from array-derived data
Background: The responses to interleukin 1 (IL-1) in human chondrocytes constitute a complex regulatory mechanism, where multiple transcription factors interact combinatorially to...
Yunlong Liu, Matthew P. Vincenti, Hiroki Yokota
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