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ASUNAM
2011
IEEE
13 years 11 months ago
Evolutionary Clustering and Analysis of Bibliographic Networks
—In this paper, we study the problem of evolutionary clustering of multi-typed objects in a heterogeneous bibliographic network. The traditional methods of homogeneous clustering...
Manish Gupta, Charu C. Aggarwal, Jiawei Han, Yizho...
ALGORITHMICA
2011
14 years 3 months ago
Algorithms for Marketing-Mix Optimization
Algorithms for determining quality/cost/price tradeoffs in saturated markets are consid-3 ered. A product is modeled by d real-valued qualities whose sum determines the unit cost ...
Joachim Gudmundsson, Pat Morin, Michiel H. M. Smid
BIOINFORMATICS
2011
14 years 6 months ago
Inverse perturbation for optimal intervention in gene regulatory networks
Motivation: Analysis and intervention in the dynamics of gene regulatory networks is at the heart of emerging efforts in the development of modern treatment of numerous ailments i...
Nidhal Bouaynaya, Roman Shterenberg, Dan Schonfeld
BMCBI
2011
14 years 6 months ago
Identifying hypermethylated CpG islands using a quantile regression model
Background: DNA methylation has been shown to play an important role in the silencing of tumor suppressor genes in various tumor types. In order to have a system-wide understandin...
Shuying Sun, Zhengyi Chen, Pearlly Yan, Yi-Wen Hua...
BMCBI
2011
14 years 6 months ago
Screening synteny blocks in pairwise genome comparisons through integer programming
Background: It is difficult to accurately interpret chromosomal correspondences such as true orthology and paralogy due to significant divergence of genomes from a common ancestor...
Haibao Tang, Eric Lyons, Brent S. Pedersen, James ...