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97
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BMCBI
2010
132views more  BMCBI 2010»
15 years 18 days ago
Protein network prediction and topological analysis in Leishmania major as a tool for drug target selection
Background: Leishmaniasis is a virulent parasitic infection that causes a worldwide disease burden. Most treatments have toxic side-effects and efficacy has decreased due to the e...
Andrés F. Flórez, Daeui Park, Jong B...
114
Voted
BMCBI
2010
97views more  BMCBI 2010»
15 years 18 days ago
Dual-functioning transcription factors in the developmental gene network of Drosophila melanogaster
Background: Quantitative models for transcriptional regulation have shown great promise for advancing our understanding of the biological mechanisms underlying gene regulation. Ho...
Denis C. Bauer, Fabian A. Buske, Timothy L. Bailey
123
Voted
BMCBI
2010
135views more  BMCBI 2010»
15 years 18 days ago
Quadratic variance models for adaptively preprocessing SELDI-TOF mass spectrometry data
Background: Surface enhanced laser desorption/ionization time-of-flight mass spectrometry (SELDI) is a proteomics tool for biomarker discovery and other high throughput applicatio...
Vincent A. Emanuele II, Brian M. Gurbaxani
104
Voted
WOTE
2010
14 years 10 months ago
On Optical Mark-Sense Scanning
Optical mark-sense scanning has lead to a resurgence in the use of paper ballots in the United States, despite a century of strong competition from paperless direct-recording votin...
Douglas W. Jones
89
Voted
GECCO
2010
Springer
188views Optimization» more  GECCO 2010»
15 years 3 months ago
Benchmarking real-coded genetic algorithm on noisy black-box optimization testbed
Originally, genetic algorithms were developed based on the binary representation of candidate solutions in which each conjectured solution is a fixed-length string of binary numb...
Thanh-Do Tran, Gang-Gyoo Jin