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BMCBI
2006
137views more  BMCBI 2006»
14 years 10 months ago
Biologically relevant effects of mRNA amplification on gene expression profiles
Background: Gene expression microarray technology permits the analysis of global gene expression profiles. The amount of sample needed limits the use of small excision biopsies an...
Rachel I. M. van Haaften, Blanche Schroen, Ben J. ...
BMCBI
2006
112views more  BMCBI 2006»
14 years 10 months ago
Assessment of the relationship between pre-chip and post-chip quality measures for Affymetrix GeneChip expression data
Background: Gene expression microarray experiments are expensive to conduct and guidelines for acceptable quality control at intermediate steps before and after the samples are hy...
Lesley Jones, Darlene R. Goldstein, Gareth P. Hugh...
BMCBI
2006
113views more  BMCBI 2006»
14 years 10 months ago
In silico discovery of human natural antisense transcripts
Background: Several high-throughput searches for ppotential natural antisense transcripts (NATs) have been performed recently, but most of the reports were focused on cis type. A ...
Yuan-Yuan Li, Lei Qin, Zong-Ming Guo, Lei Liu, Hao...
BMCBI
2006
134views more  BMCBI 2006»
14 years 10 months ago
Application of machine learning in SNP discovery
Background: Single nucleotide polymorphisms (SNP) constitute more than 90% of the genetic variation, and hence can account for most trait differences among individuals in a given ...
Lakshmi K. Matukumalli, John J. Grefenstette, Davi...
BMCBI
2006
123views more  BMCBI 2006»
14 years 10 months ago
How to decide? Different methods of calculating gene expression from short oligonucleotide array data will give different result
Background: Short oligonucleotide arrays for transcript profiling have been available for several years. Generally, raw data from these arrays are analysed with the aid of the Mic...
Frank F. Millenaar, John Okyere, Sean T. May, Mart...
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