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BMCBI
2005
108views more  BMCBI 2005»
14 years 9 months ago
The modeled structure of the RNA dependent RNA polymerase of GBV-C Virus suggests a role for motif E in Flaviviridae RNA polymer
Background: The Flaviviridae virus family includes major human and animal pathogens. The RNA dependent RNA polymerase (RdRp) plays a central role in the replication process, and t...
François Ferron, Cécile Bussetta, H&...
BMCBI
2005
108views more  BMCBI 2005»
14 years 9 months ago
A linear memory algorithm for Baum-Welch training
Background: Baum-Welch training is an expectation-maximisation algorithm for training the emission and transition probabilities of hidden Markov models in a fully automated way. I...
István Miklós, Irmtraud M. Meyer
BMCBI
2005
136views more  BMCBI 2005»
14 years 9 months ago
Identification of clustered microRNAs using an ab initio prediction method
Background: MicroRNAs (miRNAs) are endogenous 21 to 23-nucleotide RNA molecules that regulate protein-coding gene expression in plants and animals via the RNA interference pathway...
Alain Sewer, Nicodème Paul, Pablo Landgraf,...
BMCBI
2005
121views more  BMCBI 2005»
14 years 9 months ago
Comparison of seven methods for producing Affymetrix expression scores based on False Discovery Rates in disease profiling data
Background: A critical step in processing oligonucleotide microarray data is combining the information in multiple probes to produce a single number that best captures the express...
Kerby Shedden, Wei Chen, Rork Kuick, Debashis Ghos...
BMCBI
2005
143views more  BMCBI 2005»
14 years 9 months ago
Gene capture prediction and overlap estimation in EST sequencing from one or multiple libraries
Background: In expressed sequence tag (EST) sequencing, we are often interested in how many genes we can capture in an EST sample of a targeted size. This information provides ins...
Ji-Ping Z. Wang, Bruce G. Lindsay 0002, Liying Cui...
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