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2004
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2004
Springer
In nature, one finds large collections of different protein sequences exhibiting roughly the same three-dimensional structure, and this observation underpins the study of structur...
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2004
Springer
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2004
Springer
Phylogenetic hidden Markov models (phylo-HMMs) have recently been proposed as a means for addressing a multispecies version of the ab initio gene prediction problem. These models ...
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2004
Springer
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2004
Springer
The challenge of similarity search in massive DNA sequence databases has inspired major changes in BLAST-style alignment tools, which accelerate search by inspecting only pairs of...
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2004
Springer
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2004
Springer
In situ staining of a target mRNA at several time points during the development of a D. melanogaster embryo gives one a detailed spatio-temporal view of the expression pattern of ...
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2004
Springer
15 years 10 months ago
2004
Springer
Nuclear magnetic resonance (NMR) spectroscopy allows scientists to study protein structure, dynamics and interactions in solution. A necessary first step for such applications is ...