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115
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2006
Springer
16 years 23 days ago
Integrated Protein Interaction Networks for 11 Microbes
We have combined four different types of functional genomic data to create high coverage protein interaction networks for 11 microbes. Our integration algorithm naturally handles s...
Balaji S. Srinivasan, Antal F. Novak, Jason Flanni...
131
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RECOMB
2006
Springer
16 years 23 days ago
De Novo Signaling Pathway Predictions Based on Protein-Protein Interaction, Targeted Therapy and Protein Microarray Analysis
Abstract. Mapping intra-cellular signaling networks is a critical step in developing an understanding of and treatments for many devastating diseases. The predominant ways of disco...
Derek A. Ruths, Jen-Te Tseng, Luay Nakhleh, Prahla...
88
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RECOMB
2006
Springer
16 years 23 days ago
Probabilistic Paths for Protein Complex Inference
Understanding how individual proteins are organized into complexes and pathways is a significant current challenge. We introduce new algorithms to infer protein complexes by combin...
Hailiang Huang, Lan V. Zhang, Frederick P. Roth, J...
88
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RECOMB
2006
Springer
16 years 23 days ago
Markov Additive Chains and Applications to Fragment Statistics for Peptide Mass Fingerprinting
Abstract. Peptide mass fingerprinting is a technique to identify a protein from its fragment masses obtained by mass spectrometry after enzymatic digestion. Recently, much attentio...
Hans-Michael Kaltenbach, Sebastian Böcker, Sv...
111
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RECOMB
2009
Springer
15 years 7 months ago
Yeast Ancestral Genome Reconstructions: The Possibilities of Computational Methods
In 2006, a debate has risen on the question of the efficiency of bioinformatics methods to reconstruct mammalian ancestral genomes. Three years later, Gordon et al. (PLoS Genetics,...
Eric Tannier