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RECOMB
2010
Springer
14 years 7 months ago
Listing All Parsimonious Reversal Sequences: New Algorithms and Perspectives
In comparative genomics studies, finding a minimum length sequences of reversals, so called sorting by reversals, has been the topic of a huge literature. Since there are many mini...
Ghada Badr, Krister M. Swenson, David Sankoff
RECOMB
2010
Springer
14 years 7 months ago
A New Genomic Evolutionary Model for Rearrangements, Duplications, and Losses That Applies across Eukaryotes and Prokaryotes
Background: Genomic rearrangements have been studied since the beginnings of modern genetics and models for such rearrangements have been the subject of many papers over the last ...
Yu Lin, Bernard M. E. Moret
RECOMB
2010
Springer
15 years 1 months ago
MoGUL: Detecting Common Insertions and Deletions in a Population
Abstract. While the discovery of structural variants in the human population is ongoing, most methods for this task assume that the genome is sequenced to high coverage (e.g. 40x),...
Seunghak Lee, Eric Xing, Michael Brudno
RECOMB
2010
Springer
15 years 3 months ago
On the Genealogy of Asexual Diploids
Given molecular genetic data from diploid individuals that, at present, reproduce mostly or exclusively asexually without recombination, an important problem in evolutionary biolog...
Fumei Lam, Charles H. Langley, Yun S. Song
RECOMB
2010
Springer
14 years 11 months ago
Subnetwork State Functions Define Dysregulated Subnetworks in Cancer
Abstract. Emerging research demonstrates the potential of proteinprotein interaction (PPI) networks in uncovering the mechanistic bases of cancers, through identification of intera...
Salim A. Chowdhury, Rod K. Nibbe, Mark R. Chance, ...