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143
Voted
BMCBI
2010
15 years 3 months ago
2010
Background: The accumulation of high-throughput data greatly promotes computational investigation of gene function in the context of complex biological systems. However, a biologi...
124
Voted
BMCBI
2010
15 years 3 months ago
2010
Background: Tag-based techniques, such as SAGE, are commonly used to sample the mRNA pool of an organism's transcriptome. Incomplete digestion during the tag formation proces...
129
Voted
BMCBI
2010
15 years 3 months ago
2010
Background: Copy number variations (CNVs) and polymorphisms (CNPs) have only recently gained the genetic community's attention. Conservative estimates have shown that CNVs an...
149
Voted
BMCBI
2010
2010
Evaluation of methods for detection of fluorescence labeled subcellular objects in microscope images
15 years 3 months ago
Background: Several algorithms have been proposed for detecting fluorescently labeled subcellular objects in microscope images. Many of these algorithms have been designed for spe...
152
Voted
BMCBI
2010
15 years 3 months ago
2010
Background: Recently, supervised learning methods have been exploited to reconstruct gene regulatory networks from gene expression data. The reconstruction of a network is modeled...