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163
Voted
BMCBI
2008
15 years 5 months ago
2008
Background: The hierarchical clustering tree (HCT) with a dendrogram [1] and the singular value decomposition (SVD) with a dimension-reduced representative map [2] are popular met...
166
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BMCBI
2008
15 years 5 months ago
2008
Background: Illumina bead-based arrays are becoming increasingly popular due to their high degree of replication and reported high data quality. However, little attention has been...
151
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BMCBI
2008
15 years 5 months ago
2008
Background: Risk for complex disease is thought to be controlled by multiple genetic risk factors, each with small individual effects. Meta-analyses of several independent studies...
138
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BMCBI
2008
2008
RPPAML/RIMS: A metadata format and an information management system for reverse phase protein arrays
15 years 5 months ago
Background: Reverse Phase Protein Arrays (RPPA) are convenient assay platforms to investigate the presence of biomarkers in tissue lysates. As with other high-throughput technolog...
178
Voted
BMCBI
2008
15 years 5 months ago
2008
Background: Biological chemistry is very stereospecific. Nonetheless, the diastereotopic oxygen atoms of diphosphate-containing molecules in the Protein Data Bank (PDB) are often ...