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BMCBI
2005
130views more  BMCBI 2005»
14 years 9 months ago
Some statistical properties of regulatory DNA sequences, and their use in predicting regulatory regions in the Drosophila genome
Background: This paper addresses the problem of recognising DNA cis-regulatory modules which are located far from genes. Experimental procedures for this are slow and costly, and ...
Irina I. Abnizova, Rene te Boekhorst, Klaudia Walt...
BMCBI
2005
84views more  BMCBI 2005»
14 years 9 months ago
Information theory-based algorithm for in silico prediction of PCR products with whole genomic sequences as templates
Background: A new algorithm for assessing similarity between primer and template has been developed based on the hypothesis that annealing of primer to template is an information ...
Youfang Cao, Lianjie Wang, Kexue Xu, Chunhai Kou, ...
BMCBI
2005
142views more  BMCBI 2005»
14 years 9 months ago
transAlign: using amino acids to facilitate the multiple alignment of protein-coding DNA sequences
Background: Alignments of homologous DNA sequences are crucial for comparative genomics and phylogenetic analysis. However, multiple alignment represents a computationally difficu...
Olaf R. P. Bininda-Emonds
BMCBI
2005
122views more  BMCBI 2005»
14 years 9 months ago
GenClust: A genetic algorithm for clustering gene expression data
Background: Clustering is a key step in the analysis of gene expression data, and in fact, many classical clustering algorithms are used, or more innovative ones have been designe...
Vito Di Gesù, Raffaele Giancarlo, Giosu&egr...
BMCBI
2005
109views more  BMCBI 2005»
14 years 9 months ago
Genome comparison without alignment using shortest unique substrings
Background: Sequence comparison by alignment is a fundamental tool of molecular biology. In this paper we show how a number of sequence comparison tasks, including the detection o...
Bernhard Haubold, Nora Pierstorff, Friedrich M&oum...