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BMCBI
2008
138views more  BMCBI 2008»
15 years 5 months ago
Methods for simultaneously identifying coherent local clusters with smooth global patterns in gene expression profiles
Background: The hierarchical clustering tree (HCT) with a dendrogram [1] and the singular value decomposition (SVD) with a dimension-reduced representative map [2] are popular met...
Yin-Jing Tien, Yun-Shien Lee, Han-Ming Wu, Chun-Ho...
BMCBI
2008
120views more  BMCBI 2008»
15 years 5 months ago
Statistical issues in the analysis of Illumina data
Background: Illumina bead-based arrays are becoming increasingly popular due to their high degree of replication and reported high data quality. However, little attention has been...
Mark J. Dunning, Nuno L. Barbosa-Morais, Andy G. L...
BMCBI
2008
160views more  BMCBI 2008»
15 years 5 months ago
A comparison of four clustering methods for brain expression microarray data
Background: DNA microarrays, which determine the expression levels of tens of thousands of genes from a sample, are an important research tool. However, the volume of data they pr...
Alexander L. Richards, Peter Holmans, Michael C. O...
BMCBI
2008
138views more  BMCBI 2008»
15 years 5 months ago
M-BISON: Microarray-based integration of data sources using networks
Background: The accurate detection of differentially expressed (DE) genes has become a central task in microarray analysis. Unfortunately, the noise level and experimental variabi...
Bernie J. Daigle Jr., Russ B. Altman
BMCBI
2008
107views more  BMCBI 2008»
15 years 5 months ago
Extended Newick: it is time for a standard representation of phylogenetic networks
Background: Phylogenetic trees resulting from molecular phylogenetic analysis are available in Newick format from specialized databases but when it comes to phylogenetic networks,...
Gabriel Cardona, Francesc Rosselló, Gabriel...