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153
Voted
BMCBI
2011
14 years 10 months ago
2011
Background: Visualization of orthogonal (disjoint) or overlapping datasets is a common task in bioinformatics. Few tools exist to automate the generation of extensively-customizab...
168
Voted
BMCBI
2011
14 years 10 months ago
2011
Background: Accurate identification of protein domain boundaries is useful for protein structure determination and prediction. However, predicting protein domain boundaries from a...
192
Voted
BMCBI
2011
14 years 10 months ago
2011
Background: Molecular database search tools need statistical models to assess the significance for the resulting hits. In the classical approach one asks the question how probable...
140
Voted
BMCBI
2011
14 years 10 months ago
2011
Background: Alternative splicing (AS) is a process which generates several distinct mRNA isoforms from the same gene by splicing different portions out of the precursor transcript...
183
Voted
BMCBI
2011
14 years 10 months ago
2011
Background: In the last decades, microarray technology has spread, leading to a dramatic increase of publicly available datasets. The first statistical tools developed were focuse...