213
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BMCBI
2011
15 years 1 months ago
2011
Background: Discovery of biomarkers that are correlated with therapy response and thus with survival is an important goal of medical research on severe diseases, e.g. cancer. Freq...
231
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BMCBI
2011
15 years 1 months ago
2011
Background: Linkage Disequilibrium (LD) bin-tagging algorithms identify a reduced set of tag SNPs that can capture the genetic variation in a population without genotyping every s...
238
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BMCBI
2011
15 years 1 months ago
2011
Background: The Monte Carlo simulation of sequence evolution is routinely used to assess the performance of phylogenetic inference methods and sequence alignment algorithms. Progr...
251
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BMCBI
2011
15 years 1 months ago
2011
Background: OmniLog™ phenotype microarrays (PMs) have the capability to measure and compare the growth responses of biological samples upon exposure to hundreds of growth condit...
220
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BMCBI
2011
15 years 1 months ago
2011
Background: The number of gene sequences that are available for comparative genomics approaches is increasing extremely quickly. A current challenge is to be able to handle this h...
184
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BMCBI
2011
15 years 1 months ago
2011
In the article, Scanner calibration revisited, BMC Bioinformatics 2010, 11:361, Dr. Pozhitkov used the Scanner Calibration Slide, a key product of Full Moon BioSystems to generate...
262
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BMCBI
2011
15 years 1 months ago
2011
Background: Genome-wide single-nucleotide polymorphism (SNP) arrays containing hundreds of thousands of SNPs from the human genome have proven useful for studying important human ...
248
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BMCBI
2011
15 years 1 months ago
2011
Background: The prediction of the structure of large RNAs remains a particular challenge in bioinformatics, due to the computational complexity and low levels of accuracy of state...
228
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BMCBI
2011
15 years 1 months ago
2011
Background: Recently we have witnessed a surge of interest in using genome-wide association studies (GWAS) to discover the genetic basis of complex diseases. Many genetic variatio...