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CANDC
2005
ACM
13 years 6 months ago
Gene selection from microarray data for cancer classification - a machine learning approach
A DNA microarray can track the expression levels of thousands of genes simultaneously. Previous research has demonstrated that this technology can be useful in the classification ...
Yu Wang 0008, Igor V. Tetko, Mark A. Hall, Eibe Fr...
CANDC
2005
ACM
13 years 6 months ago
Assessment of chemical libraries for their druggability
High throughput virtual screening is acknowledged as the initial means for identifying hit compounds that will be eventually transformed to leads or drug candidates. To improve qu...
Suzanne W. Sirois, George Hatzakis, Dongqing Wei, ...
CANDC
2005
ACM
13 years 6 months ago
A family of metrics for biopolymers based on counting independent sets
We introduce a new family of metrics for graphs of fixed size, based on counting-independent sets. Our definition is simpler and easier to e than the edge ideal metric family defi...
Jairo Rocha, Mercè Llabrés, Ricardo ...
CANDC
2005
ACM
13 years 6 months ago
Comments on selected fundamental aspects of microarray analysis
Microarrays are becoming a ubiquitous tool of research in life sciences. However, the working principles of microarray-based methodologies are often misunderstood or apparently ig...
Alessandra Riva, Anne-Sophie Carpentier, Bruno Tor...
CANDC
2005
ACM
13 years 6 months ago
Overlapping genes in vertebrate genomes
Overlapping genes in mammalian genomes are unexpected phenomena even though hundreds of pairs of protein coding overlapping genes have been reported so far. Overlapping genes can ...
Izabela Makalowska, Chiao-Feng Lin, Wojciech Makal...
CANDC
2005
ACM
13 years 6 months ago
Latent periodicity of serine-threonine and tyrosine protein kinases and other protein families
We identified latent periodicity in catalytic domains of approximately 85% of annotated serine
Andrew A. Laskin, Nikolay A. Kudryashov, Konstanti...
CANDC
2005
ACM
13 years 6 months ago
Supporting reflective practice in creativity education
In this study, we design a learning environment to foster participants' creative attitude and evaluate its effectiveness in a university class. Our educational program consis...
Norio Ishii, Kazuhisa Miwa
CANDC
2007
ACM
13 years 6 months ago
Chromosome segregation in Escherichia coli division: A free energy-driven string model
Although the mechanisms of eukaryotic chromosome segregation and cell division have been elucidated to a certain extent, those for bacteria remain largely unknown. Here we present...
Jianmiao Fan, Kagan Tuncay, Peter J. Ortoleva