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BIB
2006
150views more  BIB 2006»
13 years 6 months ago
Open source tools and toolkits for bioinformatics: significance, and where are we?
This review summarizes important work in open-source bioinformatics software that has occurred over the past couple of years. The survey is intended to illustrate how programs and...
Jason E. Stajich, Hilmar Lapp
BIB
2006
169views more  BIB 2006»
13 years 6 months ago
Bio-ontologies: current trends and future directions
: In recent years, as a knowledge-based discipline, bioinformatics has moved to make its knowledge more computationally amenable. After its beginnings in the disciplines as a techn...
Olivier Bodenreider, Robert Stevens
BIB
2006
172views more  BIB 2006»
13 years 6 months ago
Advances in the Exon-Intron Database (EID)
Investigation of exon^intron gene structures is a non-trivial task due to enormous expansions of the eukaryotic genomes, great variety of gene forms, and the imperfectness in sequ...
Valery Shepelev, Alexei Fedorov
BIB
2006
54views more  BIB 2006»
13 years 6 months ago
Machine learning in bioinformatics
Pedro Larrañaga, Borja Calvo, Roberto Santa...
BIB
2006
113views more  BIB 2006»
13 years 6 months ago
Application of wavelet-based tools to study the dynamics of biological processes
The article makes use of three different examples (sensory information processing in the rat trigeminal complex, intracellular interaction in snail neurons and multimodal dynamics...
Alexey N. Pavlov, Valeri A. Makarov, Erik Mosekild...
BIB
2006
141views more  BIB 2006»
13 years 6 months ago
Statistical significance in biological sequence analysis
One of the major goals of computational sequence analysis is to find sequence similarities, which could serve as evidence of structural and functional conservation, as well as of ...
Alexander Yu. Mitrophanov, Mark Borodovsky
BIB
2006
84views more  BIB 2006»
13 years 6 months ago
Computational methodologies for modelling, analysis and simulation of signalling networks
This article is a critical review of computational techniques used to model, analyse and simulate signalling networks. We propose a conceptual framework, and discuss the role of s...
David R. Gilbert, Hendrik Fuß, Xu Gu, Richar...
BIB
2006
69views more  BIB 2006»
13 years 6 months ago
Flux balance analysis in the era of metabolomics
Flux balance analysis (FBA) has emerged as an effective means to analyse biological networks in a quantitative manner. Much progress has been made on the extension of FBA to incor...
Jong Min Lee, Erwin P. Gianchandani, Jason A. Papi...