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BIB
2008
77views more  BIB 2008»
13 years 6 months ago
Experience using web services for biological sequence analysis
Programmatic access to data and tools through the web using so-called web services has an important role to play in bioinformatics. In this article, we discuss the most popular ap...
Heinz Stockinger, Teresa K. Attwood, Shahid Nadeem...
BIB
2008
108views more  BIB 2008»
13 years 6 months ago
Biobanking for Europe
Biobanks are well-organized resources comprising biological samples and associated information that are accessible to scientific investigation. Across Europe, millions of samples ...
Martin Yuille, Gert-Jan B. van Ommen, Christian Br...
BIB
2008
93views more  BIB 2008»
13 years 6 months ago
A structured approach for the engineering of biochemical network models, illustrated for signalling pathways
Quantitative models of biochemical networks (signal transduction cascades, metabolic pathways, gene regulatory circuits) are a central component of modern systems biology. Buildin...
Rainer Breitling, David Gilbert, Monika Heiner, Ri...
BIB
2008
106views more  BIB 2008»
13 years 6 months ago
Biodiversity informatics: the challenge of linking data and the role of shared identifiers
A major challenge facing biodiversity informatics is integrating data stored in widely distributed databases. Initial efforts have relied on taxonomic names as the shared identifi...
Roderic D. M. Page
BIB
2008
141views more  BIB 2008»
13 years 6 months ago
Detecting short tandem repeats from genome data: opening the software black box
Short tandem repeats, specifically microsatellites, are widely used genetic markers, associated with human genetic diseases, and play an important role in various regulatory mecha...
Angelika Merkel, Neil Gemmell
BIB
2008
74views more  BIB 2008»
13 years 6 months ago
The relative value of operon predictions
For most organisms, computational operon predictions are the only source of genome-wide operon information. Operon prediction methods described in literature are based on (a combi...
Rutger W. W. Brouwer, Oscar P. Kuipers, Sacha A. F...
BIB
2008
113views more  BIB 2008»
13 years 6 months ago
Identification of replication origins in prokaryotic genomes
The availability of hundreds of complete bacterial genomes has created new challenges and simultaneously opportunities for bioinformatics. In the area of statistical analysis of g...
Natalia V. Sernova, Mikhail S. Gelfand
BIB
2008
145views more  BIB 2008»
13 years 6 months ago
Biomedical ontologies: a functional perspective
The information explosion in biology makes it difficult for researchers to stay abreast of current biomedical knowledge and to make sense of the massive amounts of online informat...
Daniel L. Rubin, Nigam Shah, Natalya Fridman Noy
BIB
2008
109views more  BIB 2008»
13 years 6 months ago
Computational intelligence approaches for pattern discovery in biological systems
Biology, chemistry and medicine are faced by tremendous challenges caused by an overwhelming amount of data and the need for rapid interpretation. Computational intelligence (CI) ...
Gary B. Fogel
BIB
2008
86views more  BIB 2008»
13 years 6 months ago
Recent developments in the MAFFT multiple sequence alignment program
The accuracy and scalability of multiple sequence alignment (MSA) of DNAs and proteins have long been and are still important issues in bioinformatics. To rapidly construct a reas...
Kazutaka Katoh, Hiroyuki Toh