11 years 7 months ago
 Beyond Graphs: A New Synthesis.
Artificial neural networks, electronic circuits, and gene networks are some examples of systems that can be modeled as networks, that is, as collections of interconnected nodes. I...
Mattiussi, Claudio, Dürr, Peter, Marbach, Daniel ...
152views Education» more  TFS 2010»
12 years 4 months ago
Robust Optimal Reference-Tracking Design Method for Stochastic Synthetic Biology Systems: T-S Fuzzy Approach
At present, the development in the nascent field of synthetic gene networks is still difficult. Most newly created gene networks are nonfunctioning due to intrinsic parameter fluct...
Bor-Sen Chen, Chih-Hung Wu
80views more  NAR 2002»
12 years 9 months ago
GeneNet: a database on structure and functional organisation of gene networks
The GeneNet database is designed for accumulation of information on gene networks. Original technology applied in GeneNet enables description of not only a gene network structure ...
Elena A. Ananko, Nikolay L. Podkolodny, Irina L. S...
105views more  IJDMB 2008»
12 years 9 months ago
Temporal representation for gene networks: towards a qualitative temporal data mining
: Recently lots of studies aim at modeling and inferring gene networks. Modeling tools propose graphical models having almost nothing about time description of events and regards t...
Nicolas Turenne, Sylviane R. Schwer
118views more  BMCBI 2006»
12 years 9 months ago
Identification of gene expression patterns using planned linear contrasts
Background: In gene networks, the timing of significant changes in the expression level of each gene may be the most critical information in time course expression profiles. With ...
Hao Li, Constance L. Wood, Yushu Liu, Thomas V. Ge...
118views more  BMCBI 2008»
12 years 9 months ago
Inferring transcriptional compensation interactions in yeast via stepwise structure equation modeling
Background: With the abundant information produced by microarray technology, various approaches have been proposed to infer transcriptional regulatory networks. However, few appro...
Grace S. Shieh, Chung-Ming Chen, Ching-Yun Yu, Jui...
13 years 1 months ago
Residual Bootstrapping and Median Filtering for Robust Estimation of Gene Networks from Microarray Data
We propose a robust estimation method of gene networks based on microarray gene expression data. It is well-known that microarray data contain a large amount of noise and some outl...
Seiya Imoto, Tomoyuki Higuchi, SunYong Kim, Euna J...
175views VLSI» more  GLVLSI 2003»
13 years 2 months ago
A custom FPGA for the simulation of gene regulatory networks
We present a unique FPGA that uses a mix of digital and large-signal analog computation for the simulation of gene regulatory networks. The prototype IC consists of a 4x5 array of...
Ilias Tagkopoulos, Charles A. Zukowski, German Cav...
153views Bioinformatics» more  CSB 2003»
13 years 3 months ago
Combining Microarrays and Biological Knowledge for Estimating Gene Networks via Bayesian Networks
We propose a statistical method for estimating a gene network based on Bayesian networks from microarray gene expression data together with biological knowledge including protein-...
Seiya Imoto, Tomoyuki Higuchi, Takao Goto, Kousuke...
13 years 4 months ago
Noise suppression in auto-regulatory gene networks
— Living cells are characterized by small populations of key molecular components that have large stochastic noise associated with them. Various gene network motifs exists within...
Abhyudai Singh, João Pedro Hespanha