117views more  NAR 2007»
13 years 7 months ago
FGF: A web tool for Fishing Gene Family in a whole genome database
Gene duplication is an important process in evolution. The availability of genome sequences of a number of organisms has made it possible to conduct comprehensive searches for dup...
Hongkun Zheng, Junjie Shi, Xiaodong Fang, Yuan Li,...
84views more  BMCBI 2005»
13 years 7 months ago
A method of precise mRNA/DNA homology-based gene structure prediction
Background: Accurate and automatic gene finding and structural prediction is a common problem in bioinformatics, and applications need to be capable of handling non-canonical spli...
Alexander G. Churbanov, Mark Pauley, Daniel Quest,...
160views more  BMCBI 2006»
13 years 7 months ago
Gene prediction in eukaryotes with a generalized hidden Markov model that uses hints from external sources
Background: In order to improve gene prediction, extrinsic evidence on the gene structure can be collected from various sources of information such as genome-genome comparisons an...
Mario Stanke, Oliver Schöffmann, Burkhard Mor...
118views more  BMCBI 2008»
13 years 7 months ago
MetWAMer: eukaryotic translation initiation site prediction
Background: Translation initiation site (TIS) identification is an important aspect of the gene annotation process, requisite for the accurate delineation of protein sequences fro...
Michael E. Sparks, Volker Brendel
97views Combinatorics» more  CPM 2005»
14 years 1 months ago
On the Complexity of Sparse Exon Assembly
Gene structure prediction is one of the most important problems in computational molecular biology. It involves two steps: the first is finding the evidence (e.g. predicting spl...
Carmel Kent, Gad M. Landau, Michal Ziv-Ukelson