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88
Voted
JCB
2006
138views more  JCB 2006»
14 years 10 months ago
Recognition and Classification of Histones Using Support Vector Machine
Histones are DNA-binding proteins found in the chromatin of all eukaryotic cells. They are highly conserved and can be grouped into five major classes: H1/H5, H2A, H2B, H3, and H4...
Manoj Bhasin, Ellis L. Reinherz, Pedro A. Reche
75
Voted
BMCBI
2010
109views more  BMCBI 2010»
14 years 11 months ago
Application of machine learning methods to histone methylation ChIP-Seq data reveals H4R3me2 globally represses gene expression
Background: In the last decade, biochemical studies have revealed that epigenetic modifications including histone modifications, histone variants and DNA methylation form a comple...
Xiaojiang Xu, Stephen Hoang, Marty W. Mayo, Stefan...