164views Computer Vision» more  NAR 2011»
12 years 8 months ago
PCDB: a database of protein conformational diversity
PCDB ( is a database of protein conformational diversity. For each protein, the database contains the redundant compilation of all the corresponding cry...
Ezequiel I. Juritz, Sebastian Fernandez Alberti, G...
260views Computer Vision» more  NAR 2011»
12 years 8 months ago
ASD: a comprehensive database of allosteric proteins and modulators
Allostery is the most direct, rapid and efficient way of regulating protein function, ranging from the control of metabolic mechanisms to signaltransduction pathways. However, an ...
Zhimin Huang, Liang Zhu, Yan Cao, Geng Wu, Xinyi L...
120views more  BMCBI 2006»
13 years 5 months ago
SCOWLP: a web-based database for detailed characterization and visualization of protein interfaces
Background: Currently there is a strong need for methods that help to obtain an accurate description of protein interfaces in order to be able to understand the principles that go...
Joan Teyra, Andreas Doms, Michael Schroeder, M. Te...
99views more  BMCBI 2007»
13 years 5 months ago
Identifying allosteric fluctuation transitions between different protein conformational states as applied to Cyclin Dependent Ki
Background: The mechanisms underlying protein function and associated conformational change are dominated by a series of local entropy fluctuations affecting the global structure ...
Jenny Gu, Philip E. Bourne
112views Optimization» more  LION 2009»
14 years 18 hour ago
A Graph-Based Semi-supervised Algorithm for Protein Function Prediction from Interaction Maps
Abstract. Protein function prediction represents a fundamental challenge in bioinformatics. The increasing availability of proteomics network data has enabled the development of se...
Valerio Freschi